Declinol, A Complex Containing Kudzu, Bitter Herbs Gentian, Tangerine Peeland Bupleurum, Significantly Reduced Alcohol Use Disorders Identification Test Audit Scores In Moderate To Heavy Drinkers.
People have used kudzu root in Eastern medicine for many years. More recently, kudzu root has made its way to Western countries as an herbal supplement. Research on kudzu for symptoms of menopause has been conflicting. Some research suggests that Transitional living taking kudzu by mouth can reduce hot flashes and improve vaginal dryness in women going through menopause. Other research shows that taking kudzu does not affect sex hormone levels, blood fat levels, bone density, or other symptoms of menopause.
The vine completely engulfs nonwooded areas but it also grows over wooded areas on which it produces large impenetrable masses and completely envelops trees and other plants, killing them all by shutting out all sunlight. Kudzu vine is now widely distributed in the United States, including all the southeast, north to Massachusetts and Illinois, and west to Texas and Oklahoma. Approximately 2,000,000 acres of forest land are covered by Kudzu vine. Development of a recognized, validated testing method and threshold equol value or equol-to-daidzein ratio will aid future interpretation of evidence. In daidzin , the link between daidzein and glucose is a COC bond, whereas in puerarin , it is a CC bond. Whereas the B-ring in flavones is in the 2-position (e.g., apigenin, A), for isoflavones it is in the 3-position (e.g., genistein, B).
Analyzing Ingredients In Dietary Supplements And Their Metabolites
They also drank less than people who had taken the placebo. While this theory may sound strange—considering that kudzu is often sold as a hangover cure—it turns out that different parts of the plant have different effects. While kudzu flowers can reduce acetaldehyde, the root does the opposite. The result may be that people who drink after taking kudzu have worse hangovers, or feel hangover symptoms earlier. Although more studies are still needed, kudzu looks promising as a medicine for reducing alcohol intake.
- Other research shows that taking kudzu does not affect sex hormone levels, blood fat levels, bone density, or other symptoms of menopause.
- For this reason, continuing relapse prevention therapy is your best chance at maintaining your recovery.
- These trials proved that the drug could decrease alcohol cravings.
- One of the herbals in Declincol, Gentian, is considered the king of the bitter herbs.
Declinol utilizes a proprietary and patent-pending encapsulation technology that enhances the absorption and bio-availability of its herbal compounds. The active ingredients are all encapsulated, or enveloped, using specific processing techniques, within phosphatidyl choline based spheres that act as transport vehicles. The process mimics natural actions that take place within the gut to enable proper absorption of nutrients, especially phyto-nutrients and fat soluble vitamins. The body’s own process in this regard creates micelles, single layer or unilamellar spheres in the size range of approximately 100 nanometers that typically can transport single nutrients. However due to dietary and physiological inefficiency, this process can often be hampered. The technology utilized with Declinol creates multi-layer or multi-lamellar spheres that are readily available and can transport multiple nutrients simultaneously.
Interested In Changing Your Relationship With Alcohol?
“The fact that participants experienced a rapid rise in blood alcohol levels when pre-treated with kudzu has no apparent explanation and therefore requires additional research,” said Penetar. For the researchers, the next step is to determine if kudzu alters regional brain blood flow using an fMRI. In this recent study, the researchers gave twelve participants different schedules of placebo or kudzu pills, and Sober living houses then observed the effects of drinking a set amount of vodka. They tested steadiness of gait, body sway, how well participants could stand upright, and how drunk they said they felt, among other factors. The researchers found that these types of responses were not intensified if participants had taken kudzu, suggesting that the drug does not work by increasing the intensity or duration of alcohol’s effects.
This article describes some natural treatments to support AUD treatment. It also explains why it’s important to find effective treatments. Whatever treatments you choose, make sure to discuss the benefits and risks with your healthcare team. These compounds are believed to increase blood flow to the brain, which can cause alcohol to affect the nervous system more quickly. This in turn can increase the speed with which the brain decides you’ve had too much, causing you to slow down and drink less.
“It is also possible that there is another, as yet undiscovered compound in the mixture that accounts for the effects. Thus, the mechanism of action of the kudzu extract remains unknown.” Is one of the earliest medicinal plants used in traditional Chinese medicine.
You may be wondering how people use kudzu root and what to know when considering whether to give it a try. EMedicineHealth does not provide medical advice, diagnosis or treatment.
What Medications Help People Quit Drinking?
Traditional Chinese medicine, animal research, and some preliminary studies have found extracts of this herb may help reduce alcohol cravings, though some studies have not shown benefit. Some evidence suggests kudzu root may help with liver damage, while other preliminary evidence suggests it may cause liver injury in certain cases. Scientists need to do more research on the effects of kudzu root in humans to investigate these effects in the liver. Another study found that people who took puerarin, an isoflavone extract from the kudzu plant, prior to drinking took longer to consume alcoholic beverages . No side effects have been reported in clinical studies when kudzu is taken by mouth. There is, however, one case report of allergic reaction following use of a combination herbal product containing kudzu . Another report suggests that taking kudzu root by mouth might cause liver damage.
So, if you want to make alcohol cravings easier to cope with, you should have a routine of natural ways to stop alcohol cravings. Meditation allows you to calm your mind and body and connect with yourself. Mindfulness and meditation can help avoid reacting to alcohol cravings and help in breaking the alcohol habit. After you remind yourself why you quit drinking alcohol, write down the consequences if you start drinking again. Of all the home remedies to stop drinking alcohol, pulling at your heartstrings can sometimes be all it takes not to drink.
The new study has a good research design, he says, but a very small sample size. The National Institute on Alcohol Abuse and Alcoholism funded the study. One study co-author is a member of the scientific advisory board at Natural Pharmacia International. The lab-turned-apartment had a reclining chair, TV, DVD player, and a refrigerator stocked with each person’s favorite beer. Shen XL, Witt MR, Nielsen M, Sterner O. Inhibition of flunitrazepam binding to rat brain membranes in vitro by puerearin and daidzein. The room contained a small sink with an under-the-counter refrigerator where the beverages were kept.
Medicines for alcoholism also give patients an incentive to remain sober. But it helps some people remain sober by making the experience of drinking alcohol extremely undesirable. Soon after, the FDA approved disulfiram to treat alcohol dependence. Wyeth-Ayerst Laboratories first produced the medication under the brand name Antabuse.
Kudzu Recovery: Conclusion
Some common applications include treating fevers and easing symptoms of diabetes. Now kudzu’s popularity is also picking up in the Western world as a wellness supplement. It’s best to speak with your healthcare provider to determine whether kudzu root could interact with any medications you’re taking. One animal study found that isoorientin, a compound isolated from kudzu root, boosted antioxidant levels and reduced inflammation markers in mice with swollen paws .
At the time of writing, there were no well-known side effects caused by this supplement. For an herb, supported by traditional use but minimal or no scientific evidence. In Sociology from the University of Sussex in the United Kingdom. After working in digital marketing and copywriting after graduating, how to reduce alcohol cravings naturally she transitioned to full-time freelance writing and editing. Ellie has a passion for social causes and writes regularly on issues of homelessness in which physical and mental health disorders are common among rough sleepers. L-glutamine is an amino acid that the body naturally creates.
It has been used in Chinese medicine since at least 200 BC. Declinol is blended formula developed by one of us consisting of a number of key ingredients such as Kudzu, Bitter Herbs and Bupleurum and other herbals . The primary indication of this complex and the pilot study described in this article involve Declinol’s effect in alcoholism. Because this the first report on Declinol, we are compelled to briefly review these three important ingredients role in alcoholism including both central and peripheral actions. Replacing alcohol with a healthy self-care ritual can ease alcohol cravings and help in breaking the alcohol habit. We have all tried home remedies before going to the doctor.
Fetal alcohol syndrome causes irreversible physical and mental disabilities. The only safe way to protect against damage to the baby is not to drink during pregnancy, or even if you are trying to become pregnant. Never drink and drive or allow your teenager to be driven in the car by someone who has been drinking. Monitor your teenager for aggressive behavior, feelings of anger or depression, and poor school performance. If any of these develop, consider whether alcohol may be responsible. PeaceHealth endeavors to provide comprehensive health care information, however some topics in this database describe services and procedures not offered by our providers or within our facilities. All Alcoholrehabhelp content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
All of the above mentioned mechanisms, with the exception of a disulfiram-like one, require repeated administration and time to develop. Since consuming alcohol while taking kudzu extract is not aversive, another explanation is necessary to account for the extremely fast onset of action observed in the present study.
Medical & Clinical Conferences
Human clinical trials were executed in the late 80s and early 90s. These trials proved that the drug could decrease alcohol cravings. They can also lessen relapse rates in alcoholics when combined with psychosocial therapy.
The use of kudzu for alcoholism originated in China around 600 A.D. The Chinese noticed that people who consumed the plant started to drink less. According to traditional Chinese medicine, kudzu has cooling properties that balance the heat and false energy created by alcohol. Keung, not directly involved in Lukas’ study, said he has extracted a compound from kudzu root that he hopes to turn into a drug for reducing alcoholics’ cravings. Lukas was not certain why but speculated that kudzu increases blood alcohol levels and speeds up its effects. More simply put, the subjects needed fewer beers to feel drunk. The number of participants who drank each available beer during the 1.5 hour drinking session following administration of placebo or kudzu.
Author: Theresa Parisi